University at Buffalo School of Medicine - Yearbook (Buffalo, NY)

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I L tl -J. I. I ir L' TRANSPORT OF INERT GASES THROUGH THE SKIN AT VARYING AM- BIENT TEMPERATURES - Roberf A. Klocke, Gail H. Gurfner The fransporf of inerf gas from fhe blood fhrough fhe skin info an airfighf chamber was measured af various ambienf 'Iemperafures in a subiecf breafhing a mix- fure of oxygen and iner'I' gas. Comparison of fhe rafes of fransporf of argon, helium and nifrogen showed fhaf gas fransporf fhrough fhe skin is Iimifed by fhe skin dif- fusion barrier and is unaffecfed by fhe fofal cufaneous blood flow. Laferal sliding flap surgery has been per- formed on humans fo correcf undesirable aesfhefics in fhe mandibular incisar region. Excepf for fhe aesfhefic improvemenfs ac- complished, fhe consequences of fhis pro- cedure bave nof been adequafel invesfi- gafed. Therefore, fhis sfudy on fhe maxil- Iary canine region in dogs was designed fo provide hisfologic informafion concern- ing fhe healing process affer Iaferal slid- ing flap surgery. This sfudy was underfaken by Mr. Ernesf LaLonde Denf. '6I. Affer only 8 monfhs of invesfigafion, fhe resulfs are yef inconclu- sive, buf bear ouf Dr. Friedman's fhesis on fissue healing. Mr. LaLonde expecfs fo fre PRODUCTION OF DEEP HYPOTHERM- IA IN DOGS AND TOTAL CIRCULA- TORY ARREST BY BLOOD STREAM COOLING WITH THE MACNEILL DI- ALYZER - Sefh Resnicoff Wifh body femperafure af IOOC. if was shown fhaf fhe bod could folerafe one hour of fofal circullafor arresl' wifhouf anoxic damage. This enables fhe surgeon fo perform infricafe cardiac surgery in a dry, mofionless hearf. WH.. summarize his findings by June '62. i ,anu- ,pnml ETHYL ETHER CONTENT IN BLOOD AS DETERMINED BY GAS CHROMATOGRAPHY - John W. Cudmore In recenf years, if has been fhe aim of Dr. T. H. Noehren, Assisfanf Professor of Infernal Medicine, fo perfecf a complefe fesf of cardio-pulmonary funclion. Basic fo fhis procedure was fhe developmenf of a quick and accurafe mefhod of blood efher deferminafion. - In Anesfhesiology, Vol. 22, No. 4, July-Augusf I96I, a mefhod for fhe anal sis of efhyl efher confenf in blood by gas chromafograplny was published. The gas is ex- fracfed in 'I'he fonomefer of a Van Slyke apparafus and, :ffer column separafion, is analyzed by fhermal conduc- lvl y. MMG' Roberf Wilson sfudied fhe circulafing levels of anfi- hemophilic globulin in bofh normal and hemophilic sub- Ecfs under a granf from 'Ihe Nafional Insfifufes of Healfh. is subiecfs were eighf members of fhe Senior Class. Affer fracfionizafion of a blood sample fo obfain pure anfi-hemophilic globulin, serial dilufions againsf a known quanhfy would give fhe subiecf's level. By drawing samples periodically, he showed fhaf fhis level changes quanflfafively from monfh fo monfh. He presenfed his sfudyi af fhe I02nd Annual Session of fhe ADA in Phila- delp ia.

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rggv 'J i 1. L. to R., Seated: S. Resnicoff, A. Pohl, F. Ehrlich, H. Scheuermann, G. Gurtner, 2nd Row: l. Reilly, E. Means R. Lederman, V. Verral, l. Callanan, C. Ladoulis, G. Cohen. 3rd Row: J. Gerbasi, H. Glucksberg, P. Sussman, S. Katz V. Frantz, S. Kaiser. The James A. Gibson Anatomical Society was founded by the Medical Classes of I9l9 and I920 in honor of the late Professor of Anatomy and Secretary of the Medical Faculty. The Society has as its objectives the promotion of superior scholar- ship among medical students and stimulation of interest in scientific investigation. ln accordance with these aims, fourteen students are chosen from the sophomore class in recognition of superior academic accdmplishments in the freshman year, particularly in the subiects of gross, microscopic and neural anatomy. The Society also sponsors a series of lectures at which distinguished speakers vaddress the mem- bership and guests. ln I96l-I962 Dr. Berkeley Zinn spolce on the Segmental Anatomy of the Lung and Dr. Joseph M. Dziob on Surgery of the Hand. At the end of the academic year, a banquet is tendered in honor of the new members and they are formally welcomed into the Society. GIBSON SOCIETY OFFICERS FOR I9bI: President--Frank Ehrlich, Ist Vice President-John Stumpf, 2nd Vice President- John Schriver, Secretary-Henry Scheuermann, Treasurer-Richard DuBois. Qdson nafomical Society

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The following fopics were sfudied by Ronald Dozorefz in associafion wifh Dr. Julian Ambrus af fhe Roswell Park Me- morial lnsfifufe. The value of fibrinolysin fherapy for peri- pheral vascular fhrombosis and hyaline membrane disease. A double-blind sfudy evaluafing combi- nafion drug fherapy analgesia in cancer pafienfs. The anfi-cancer value of AB-l32, one of a series of dual anfagonisfs. ,599 PHARMACOLOGICAL STUDY - Paul Loree Mr. Wiggin, sfudying under Dr. House- mann of fhe Pharmacology Deparfrnenf, worked ,wifh immafure rafs in an efforf fo produce fhe hypofhyroid sfafe by iniecfing 300 microcuries of I131 infraperifoneally. He 'Found fhaf in his lof of l00 rafs fhaf 'lhe basal mefabolism rafe, body weighf, and hearl' rafe significanfly decreased af- fer fwo and one-half weeks, and fhaf fhis mefhod seemed superior fo surgery or fhe use of anfifhyroid drugs. '27 l PURIFICATION OF THYROID PROTEINS BY COLUMN CHROMOTOGRAPHY Joseph Armenia By sfepwise elufion column chromof09' raphy on diefhylaminoefhyl cellulose fhyr0' globulin was purified fo approximafely 992 ulfracenfrifugal homogeneify from 6 crude saline exfracf of fhyroid gland. L TISSUE IMMUNIZATION - Roberl' Genco. Tissue immunizafion sfudies were conducfecl in fhe lab- The long acfing coronary vasodilafor enfaeryfhrifal fefranifrafe produces a sfafisfically signifiicanf decrease in The nifroglycerine requiremenfs of pafienfs wifh an- gina pecforis. Addifion of franquilizers or phenobarbifal fails fo enhance fhe acfion of fhe drug alone. Six hundred pafienfs freafed in fhe psychiafric service of E. J. Meyer Memorial Hospifal wifh Promazine were found fo have neifher physical nor chemical evidence of he afofoxicify or bone marrow cle ression. These side eflzcfs have been reporfed for chloor romazine. Trans- ienf hypofension was fhe only side eigecl' presenf wifh Promazine as used on fhis service according fo fhe manu- facl'urer's suggesfed dosage schedule. II6 orafories of Dr. Ernesf Beufuer in fhe Deparfmenf of Bac- feriology and Immunology. Animal immunizafion wifh salivar glands was fhe basic area of sfudy. lf was found fhal' afler immunizafion wifh submaxillary glands, rab- bifs may produce anfibodies fhaf acf in vifro wifh some of fheir own salivary glands. This fype of anfibody is referred fo as an au'l'oan'l'ibody. The formafion of aufoanfibodies is a remarkable phe- nomena and has been shown fo be associafed wifh sev- eral human diseases, some of which are of proven aufo- immune efiology. These experimenfs were direcfed af elucidafing Siorgren's Syndrome, a human disease char- acferized by lack of salivary and lacrimal secrefions.