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Page 33 text:
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PHARMACOLOGY J. Bryan Smith, Ph.D. Chairperson Martin W. Adler, Ph.D. Barrie Ashby, Ph.D. Martin Black, M.D. Alan Cowan, Ph.D. James L. Daniel, Ph.D. Concetta Harakal. Ph.D. Lee-Yuan Liu-Chen, Ph.D. James G. McElligott, Ph.D. Michael Ruggieri, Ph.D. Michael A. Sirover, Ph.D. Gerald H. Sterling, Ph.D. Ronald J. Tallarida, Ph.D. George D. V. Van Rossum, Ph.D. Opioid receptor Bindlna of naloxone does not activate receptor and. therefore, naloxone reverses the effects of opioid agonists, such as morpine and heroin Temple E.R.’s wake up call Dr. Sterling
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Page 34 text:
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Dr. Sterling and Dr. Tallarida assoc. log--------------= pKa - pH dissoc. HA === h+ + A-B- + H+ ==== BH NH3 + H+ === NH4 + Top 5 Most Remembered Pharm Facts: 1. There arc good drugs and bad drugs 2. Caffeine is a very good drug 3. Beer isn't half bad cither 4. Lecture + slides = instant sedation 5. They lied: Biochent does show up again INCREASED RESPONSE cv Vl METHODS • HI -.. c cerebral I ARTERIAL TONE ANO 1 45CALCIUM UPTAKE I AND BINDING METHODS - II 30 Pharmacologic basis of cocaine Dr. Mills
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