St Louis College of Pharmacy - Prescripto Yearbook (St Louis, MO)

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1933 P1211 SCRIPTO taxicabs from the hotel to the magnificent Lilly Plant where we saw the process of manufacturing Insulin, Liver Extract, and other drugs and pharmaceu- tical preparations. It was a wonderful experience for all of us. We saw our small operations of the pharmaceutical laboratory carried out on a larger scale, including the manufacture of pills, tablets, capsules, ointrnents, fluid extracts, elixirs, and many other preparations too numerous to mention. At twelve- fifteen P. M. we had lunch at the Lilly cafeteria where we had our fill. After lunch, we all boarded motor busses and proceeded to the Lilly Biological Lab- oratories. This was really a sight to behold and something to marvel at. Rigid health and sanitary conditions are enforced. The buildings are kept immacu- late at all times. I We had the privilege of seeing the first step in the preparation of the vac- cine virus, that is, the vaccination of the heifer. Minute superficial scratches are made on the abdomen and the virus is rubbed in. The opportunity of seeing the removal of ten litres of blood from the jugular vein of an immune horse was granted us. This was the ninety-ninth time this particular animal had been bled. They are bled at approximately twenty-one-day intervals. Then we saw how this blood was separated, puri- fied, sterilized, and standardized. This process involves a huge expense and the utmost accuracy and precaution is absolutely necessary in all experiments. At approximately three-forty-five P. M. we left the biological farm and re- turned to the hotel where we had dinner at four-forty-five. We left Indian- apolis at six-twenty-five P. M. and arrived at St. Louis at eleven-thirty P, M., everyone having had a magnificent two-day vacation and a fairly good idea as to how the preprations which We use in filling our prescriptions are prepared on a large scale. We are grateful to Eli Lilly and Company for this wonderful opportunity they so graciously afforded us and also for the pleasant associations we enjoyed with the members of their personnel. We sincerely hope that those who have not had the opportunity to go will do so when another invitation is extended in the future and that We may some day again enjoy this privilege and pleasure. Page Nmety One

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1933 PRESCIQIPTO Page Ninety Itinerary of the 1933 Trip to Indianapolis T train time, nine A. M., April 25th, there were some seventy-five or eighty seniors and juniors, and Mr. Blankenbaker of Eli Lilly, Professor Dall- mann, Dr. DeFoe, Mr. Ferguson, and two former graduates of the College assembled at the Union Station. After an interesting, entertaining five and three-quarter hours on the train, we arrived at Indianapolis at one-forty-five P. M. We were met at the station by several members of the firm of Eli Lilly and Company. We were at once ushered to the Severin Hotel where we found all conveniences of home -including shower bath and radio service. The afternoon was spent roaming about town, some fortunate few hiring private driv-ur-self cars and the majority, not so fortunate, hoofing it. One of the most interesting sights in Indianapolis is the so-called circle, in the center of which stands a huge statueg from this central figure the streets branch out in all directions. fAn easy place to get lost-believe you mel At six P. M. we assembled in the roof garden banquet room for a delicious dinner which was followed by talks by Mr. Zink, general sales manager, and Mr. Hughes, chief research chemist for Eli Lilly and Company. At eight P. M. the banquet and speeches terminated and we were given tickets to the Indiana Theatre, which most of us made use of. The show was enjoyed by all who attended fexcept the cash customersj. Following the theatre, most of us went to the Indiana Ball Room above the theatre where we found the Indian- apolis girls to be very sociable. St. Louis was well represented. This ball room is probably one of the most beautiful in the country, being of Spanish type, balcony and all. After the dance, some attempted to obtain a little sleep. Those who didn't prevented the ones who attempted to from doing so. Up and down, all night long, was the familiar chant heard outside the portals of our emporial chambers. The following morning, all enjoyed breakfast at eight A. M. fexcept Rosen- hauer and Hewitt, who were late as usualj . At nine o'clock we proceeded in

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1933 P1?.LSCRIP'1'O Medical Therapy in 1770 N the early days of the Republic the theory and practice of medicine were still largely dominated by mediaeval tradition. Whatever treatment was in accord with authority was rational or regular and Whatever departed therefrom was empiric or quackish. The declaration of an eminent prac- titioner of the period, that he would rather be Wrong with Galen than right with any other authorityn indicates something of the resistance to innovations and of the reverence for traditional methods of practice which then largely prevailed among members of the medical profession. Judging from ancient case books, bleeding, blistering, puking, and drastic purging with heavy doses of calomel constituted the principal routine of med- ical practice. Bloodletting Was the initial treatment in almost every case, even in preg- nancy, yellow fever, consumption, broken bones, and Asiatic cholera. Even as late as 1841 a leading American exponent of the old practice declared that five-sixths of the blood was superfluous, and loaded with seeds of disease, and hence every treatment should be initiated by depletion. Bleed the patient till he is white was the admonition constantly addressed to the student of medicine, while blistering ran a close second to bloodletting, frequently car- ried to the point of suppuration and the sloughing of the broken down tissue. Medication was heroic, both in character of the remedies employed and in dosage. Tartar emetic, calomel and other drastic remedies were given in doses which to us seem perfectly enormous. Calomel was administered in doses of ten grains to a teaspoonful as compared with the present average dose of one-tenth grain, and was not considered effective until carried to the point of complete mercurialization, or salivation as it was commonly called. One authority, lVIotherby's Medical Dictionary 117751, recommended calomel in certain cases to the extent of a pound and a half in 24 hours, which, if the troy pound was meant, would be the equivalent of 86,400 modern average doses of that agent. Not only in Washington's day, but long afterward many believed that the theory and practice of medicine had reached its full measure of development. As late as 1845 one of its chosen spokesmen publicly declared that medical science does not need, or is it susceptible of, further improvement or reform. A contemporary historian also relates that it was required of every individual about to graduate at the principal medical colleges, as the condition of receiv- ing the degree of Doctor of Medicine, that he should swear to adhere to the old procedure, or forfeit his diploma. We are grateful to the American Druggist for this information, published in the February, 1933, issue. Page Nmety Two