Duke University School of Medicine - Aesculapian Yearbook (Durham, NC)

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PH 'YSIOLGGT Ss? X' as X 1 v 55 s iz its M96 ,935 sv W t dz MW V as 1, X 4 K bt :vac .vr-, . -2+ QR v's-Ac-,-M Z.,5-L,t.:,s.:Q.,1,g-,.,.tam.f-, The Department of Physiology and Pharmacology consists of a Division of Physiology and a Division of Pharmacology. Each Division seeks to provide a focus for the growth and dissemination of ideas in their re- spective disciplines within Duke University. ln order to provide for growth of new ideas in Physiology and Pharmacology, the Department is engaged in a vigorous program of research in certain aspects of these fields. In order to provide for the dissemination and communi- cation of these new ideas, the Department conducts an educational program for medical students, graduate stu- dents, post-doctoral students, and nurses. Since both of these departmental responsibilities, research and teaching, require a large and varied faculty, the Department is in the process of a substantial expansion. This expansion will be completed upon construction of a new medical sciences building which will form the first component of the new medical campus at Duke. In recognition of the fact that a few investigators working on the same problem seem to progress more effectively and happily than either a single scientist working alone or a large group, both Divisions of the Department are organized into a loose confederation of relatively autonomous laboratories. Each Laboratory is headed by a mature scientist capable of conducting a vigorous research program. Within the Division of Physiology the following Laboratories are in being: the Laboratory of Cellular Neurophysiology CChief, Asso- ciate Professor W. Moorej, Laboratory of Muscle Physiology CChief, Associate Professor P. Horowiczj, Laboratory of Molecular Physiology fChief, Associate Dix. TCJSTESCJN Professor Hluml, Laboratory of Cellular Endo- crinology fChief, Associate Professor I. Kostyoj, Labora- tory of Cardiopulmonary Physiology CChief, Associate Professor W. E. Hullj, and the Laboratory of Cellular Transport Processes CChief, Professor D. C. Tostesonj. The Division of Pharmacology presently contains one Laboratory of Biochemical Pharmacology, headed by Professor F. Bernheim. Laboratories of Circulatory, Cardiac, and Oncological Pharmacology are presently in process of formation. When the Department is at full strength in the new building, there will be nine or ten laboratories in the Division of Physiology and six labora- tories in the Division of Pharmacology. Since it is obviously impossible to represent the entire fields of Physiology and Pharmacology within any one department, the selection of the areas covered by the Laboratories mentioned above involves decisions regard- ing the most promising frontiers in the two disciplines. . ,- ,.,, , ' ff lin. Ficiinuiuczk liuiuviiiaim Du. WAYLAND HULL DR. E. Citorr LONG eiglz teen

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chemical concepts. Such experience, in the future, may well he limited to students who voluntarily so request. By the same token, in their research lahoratories, the hiochemical faculty should-and dowaddress themselves to questions which have no immediate application in medicine, hut the answers to which must. ol necessity, form the hasis for medical practice tomorrow: I-low do enzymes work? Wlizit is an antihody? llow do genes work? What factors make for the harmonious, integrated flow of metaholism which characterizes the normal cell? I-low is the potential energy of foodstufls transduced into the accomplishment of mechanical, elec- trical, osmotic, or chemical work? How are the various kinds of macromolecules made? Wlizit are the specihc functions of diverse suhcellular organelles and how are these constructed? What is the molecular basis for cellular dillerentiationF ls there a molecular liasis lor memory? These are the grand questions. The health ol the American people tomorrow will depend upon our success in linding the answers. lt is these questions which underlie the research programs ol' the faculty ol the Department ol' liiochemistry and it is the current state ol' the answers to these questions which properly constitutes the hasis for the course in hiochemistry which we oller to our students. Hopefully. we shall soon he ahle also to provide, to those students so desiring, a much more intensive experience in hiochemistry as part of their medical education. PHILIP I-I.xxn1,ER, PIID. Cfmirzmzn of lfze Dcfprzrtnzcnt lunzes B. Duke l'r0fes,v0r vu . Du. HENRY li,-XMIN DR. NIARY Biiitrsniaim Dia. WILLIQXKI LYNN .fC'l!C l1fC'C'71

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Research in the Department can be viewed as directed toward two such frontiers. First, the goal of much of the work is to increase our understanding of the molecu- lar basis of fundamental physiological processes, such as muscular contraction, nerve conduction, active trans- port, and cell division. The second frontier involves the analysis of complex integrated physiological functions such as the mechanics of respiration, the activity of the hrain, etc., with the use of modern analogue and digital computer techniques. In providing for the communication of ideas in Physi- ology and Pharmacology, the Department recognizes a primary responsibility to provide the hest possihle in- struction to First and second year medical students. In addition, it offers a vigorous educational program for graduate students who are candidates for the l'h.D. degree in Physiology or Pharmacology. The graduate program involves a general course in Physiology and Pharmacology taught from the literature, as well as courses in selected advanced aspects ol' lvoth disciplines. The advanced courses are also open to third and fourth year medical students as well as postdoctoral students. In collahoration with the Department of Electrical Engi- neering, the Department of Physiology and Pharma- cology offers a training program in Biomedical Engi- neering. The Department is also active in promoting the development of more vigorous teaching in the areas of clinical physiology and clinical pharmacology. D.-txiiit. Tos'rEsoN, M.D. ChLlliI'771L1IZ of the Deprzrtnzwzt nineteen